At the outset of this letter, there is one vital fact I would like to submit.

6 seconds sound clip from the Reefer Madness (1936) movie soundboard.

You can hear this line at 00:05:10 in the Blu-ray version of the movie.

Quote context

[...]

- This ceaseless fight against the drug traffic is directed by the Department of Narcotics, Washington.

- I have received a letter of vital importance from a member of the Narcotics Bureau.

- I'm going to read this letter to you.

- My dear Dr. Carroll...

- The suppression of the use of marihuana and of the forces lurking behind it are the most important jobs this department is now engaged in.

- At the outset of this letter, there is one vital fact I would like to submit.

- There is a powerful agency.

- I speak of the school-parent associations of this country, which can be invaluable in stamping out this scourge.

- Their help, their eternal vigilance could be the deciding factor in our fight against it.

- The weed marihuana is grown in every state in the Union.

[...]

Top rated lines from this movie

This, I understand, could be attributed to the use of marihuana. It causes errors in time and space.
Yes, I remember. Just a young boy. Under the influence of the drug, he killed his entire family with an axe.
Honest? If you were being honest with me and honest with yourself, I'm afraid you'd tell me an entirely different story.
That happened right here, to your neighbors. It is not too much to say that in your hands lies the possibility of averting other tragedies like it.
And more vicious, more deadly even than these soul-destroying drugs is the menace of marihuana.

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