You know him? Well, sure I do.
4 seconds sound clip from the It's a Wonderful Life (1946) movie soundboard.
You can hear this line at 01:57:35 in the Blu-ray version of the movie.
Quote context
[...]
- Mother, listen. Please help me. Something terrible's happened to me.
- I don't know what it is. Something's happened to everybody.
- Please let me come in, and keep me here until I get over it.
- Get over what? I don't take in strangers unless they're sent here by somebody I know.
- Well, I know everybody you know. Your brother-in-law, Uncle Billy.
- You know him? Well, sure I do.
- When did you see him last? Today over at his house.
[...]