Oh, Mother.
3 seconds sound clip from the Christmas Vacation (1989) movie soundboard.
You can hear this line at 00:18:54 in the Blu-ray version of the movie.
Quote context
[...]
- You promised. Of course I do.
- They took a pint of fluid out of my lower back.
- Do you see this mole? This mole on my neck? Think it's changing color?
- No.
- Well, you keep touching it, it gets redder.
- I got hemorrhoids. Can you believe that?
- You're not getting the garage space.
- Mom, they're not sleeping in my room. I'm gonna go crazy, Mom.
[...]